Key result
A reverse-dipper nocturnal blood pressure profile was associated with significantly higher aortic pulse wave velocity compared with dippers (P=0.005) and nondippers (P=0.006).
Why the study?
Does circadian blood pressure variation (dipper status) correlate with measures of arterial stiffness in untreated hypertensive individuals?
Population
314 untreated hypertensive individuals, mean age 48 +/- 8 years, 55% men.
Comparison
Reverse-dipping, nondipping, or extreme dipping… vs Dipping nocturnal blood pressure profile
Design
Cross-sectional
Authors
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Reverse-dipper nocturnal BP was associated with higher aortic PWV; hypothesis-generating for circadian patterns and vascular stiffness.
Cross-Sectional (n=314)
Does circadian blood pressure variation (dipper status) correlate with measures of arterial stiffness in untreated hypertensive individuals?
p-value: p=0.005 and 0.006
A reverse-dipper nocturnal blood pressure profile is associated with increased aortic pulse wave velocity, indicating greater arterial stiffness independent of traditional risk factors.
Jerrard-Dunne et al. (2007) conducted a cross-sectional in untreated hypertension (n=314). Reverse-dipper nocturnal blood pressure profile vs. Dippers and nondippers was evaluated on Aortic pulse wave velocity (PWV) (p=0.005 and 0.006). A reverse-dipper nocturnal blood pressure profile was associated with significantly higher aortic pulse wave velocity compared with dippers (P=0.005) and nondippers (P=0.006).
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