Key result
Noncontrast chest computed tomographic imaging biomarkers of metabolic syndrome, such as coronary artery calcification, have prognostic implications for major adverse cardiac events.
Why the study?
Overeating leads to physiological consequences that increase morbidity and mortality, prompting a review of the current state of the art in noncontrast chest computed tomographic imaging biomarkers of the metabolic syndrome and their prognostic significance.
What are the NCCT imaging biomarkers of metabolic syndrome and their prognostic significance?
What are the NCCT imaging biomarkers of metabolic syndrome and their prognostic significance?
Noncontrast chest CT imaging can identify biomarkers of metabolic syndrome that have prognostic implications for major adverse cardiac events, offering potential targets for AI-based longitudinal assessment.
May aid risk stratification on routine chest CT; leaves open prospective validation before guiding therapy.
There are physiological consequences of overeating that can lead to increased morbidity and mortality. The purpose of this review article is to acquaint the reader with the current state of the art in the non-cardiac-gated, noncontrast chest computed tomographic (NCCT) imaging biomarkers of the metabolic syndrome and their prognostic significance found in the lower neck and chest. NCCT imaging biomarkers associated with metabolic syndrome in the chest include premature coronary artery calcification, acceleration of large vessel arterial and valvular calcifications associated with atherosclerosis, and pulmonary arterial enlargement from pulmonary hypertension associated with sleep apnea. These easily identified imaging biomarkers have prognostic implications for major adverse cardiac events (MACE). These NCCT chest-imaging biomarkers are likely targets for artificial intelligence algorithms to harvest for longitudinal assessment of their individual and multifactorial contributions to chronic disease, MACE, and mortality. Early recognition and treatment of these common disorders may help improve patient outcomes and quality of life while decreasing medical costs.
No takes yet. Share an insight, caveat, or question.
Schlett et al. (2019) conducted a review in Obesity and Metabolic Syndrome. Noncontrast chest computed tomographic (NCCT) imaging was evaluated. Noncontrast chest computed tomographic imaging biomarkers of metabolic syndrome, such as coronary artery calcification, have prognostic implications for major adverse cardiac events.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: