What question did this study set out to answer?

Identify preoperative clinical factors and routine laboratory parameters that predict in-hospital complications and healthcare resource utilization following elective cranial neurosurgery.

May 1, 2015Journal of neurosurgeryOpen Access

Preoperative factors including advanced age, elevated CRP (>3 mg/L), and high Helsinki ASA score were associated with in-hospital systemic and infectious complications after elective craniotomy.

Q: What is the clinical evidence from this study?

Study design: Cohort. Population: Elective craniotomy for any intracranial lesion (n=418). Intervention: Preoperative risk factors (advanced age, elevated CRP, high Helsinki ASA score). Primary outcome: In-hospital mortality, systemic or infectious complications, and CNS deficits.

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Why the study?

Do preoperative assessments predict in-hospital complications in adults undergoing elective craniotomy?

Population

418 consecutive adults (≥ 18 years) undergoing elective craniotomy for any intracranial lesion

Design

Cohort

Follow-up

in-hospital

Key result

Preoperative factors including advanced age, elevated CRP (>3 mg/L), and high Helsinki ASA score were associated with in-hospital systemic and infectious complications after elective craniotomy.

Authors

ERElina Reponen MKMiikka Korja TNTomi Niemi

Discussion

Member takes

Overview

These factors may aid risk stratification; leaves open whether targeted interventions reduce complications after elective craniotomy.

Key Points

Identify preoperative clinical factors and routine laboratory parameters that predict in-hospital complications and healthcare resource utilization following elective cranial neurosurgery.
Conducted a prospective cohort study of 418 consecutive adult patients (≥ 18 years) undergoing elective craniotomy for any intracranial lesion.
Evaluated preoperative variables including routine blood tests, standard ASA status, and the Helsinki ASA classification against adverse outcomes (mortality, systemic or infectious complications, and CNS deficits) and length of stay.
Overall in-hospital mortality was 1.0%, while systemic or infectious complications occurred in 6.7% and CNS deficits in 11.2% of patients.
Advanced age (≥ 60–65 years), elevated C-reactive protein (> 3 mg/L), and high Helsinki ASA score (Class 4) were significantly associated with systemic and infectious complications, identifying one-fourth of complicated cases.
The combination of these preoperative risk factors was significantly linked to extended intensive care unit and overall hospital length of stay.

Study Design

Type

Cohort (n=418)

Structured PICO

Do preoperative assessments predict in-hospital complications in adults undergoing elective craniotomy?

Population

418 consecutive adults undergoing elective craniotomy for any intracranial lesion, evaluated for preoperative predictors of in-hospital complications.

Exposure

Preoperative assessments including patient-related data, routine blood tests, ASA Physical Status Classification, and Helsinki ASA classification

Outcome

In-hospital mortality, in-hospital systemic or infectious complications, and in-hospital CNS deficitshard clinical

Simple preoperative assessments including age, CRP, and Helsinki ASA score can identify elective craniotomy patients at high risk for in-hospital complications and extended resource use.

Cite This Study

Reponen et al. (2015) conducted a cohort in Elective craniotomy for any intracranial lesion (n=418). Preoperative risk factors (advanced age, elevated CRP, high Helsinki ASA score) was evaluated on In-hospital mortality, systemic or infectious complications, and CNS deficits. Preoperative factors including advanced age, elevated CRP (>3 mg/L), and high Helsinki ASA score were associated with in-hospital systemic and infectious complications after elective craniotomy.

synapsesocial.com/papers/6a74bccca44b96c1f7dbe03b https://doi.org/10.3171/2014.11.jns141970

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May 1, 2015Journal of neurosurgeryOpen Access

Preoperative factors including advanced age, elevated CRP (>3 mg/L), and high Helsinki ASA score were associated with in-hospital systemic and infectious complications after elective craniotomy.

View Full Paper

Ask AI

Bookmark

Why the study?

Do preoperative assessments predict in-hospital complications in adults undergoing elective craniotomy?

Population

418 consecutive adults (≥ 18 years) undergoing elective craniotomy for any intracranial lesion

Design

Cohort

Follow-up

in-hospital

Key result

Preoperative factors including advanced age, elevated CRP (>3 mg/L), and high Helsinki ASA score were associated with in-hospital systemic and infectious complications after elective craniotomy.

Authors

ERElina Reponen MKMiikka Korja TNTomi Niemi

Discussion

Member takes

Overview

These factors may aid risk stratification; leaves open whether targeted interventions reduce complications after elective craniotomy.

Key Points

Identify preoperative clinical factors and routine laboratory parameters that predict in-hospital complications and healthcare resource utilization following elective cranial neurosurgery.
Conducted a prospective cohort study of 418 consecutive adult patients (≥ 18 years) undergoing elective craniotomy for any intracranial lesion.
Evaluated preoperative variables including routine blood tests, standard ASA status, and the Helsinki ASA classification against adverse outcomes (mortality, systemic or infectious complications, and CNS deficits) and length of stay.
Overall in-hospital mortality was 1.0%, while systemic or infectious complications occurred in 6.7% and CNS deficits in 11.2% of patients.
Advanced age (≥ 60–65 years), elevated C-reactive protein (> 3 mg/L), and high Helsinki ASA score (Class 4) were significantly associated with systemic and infectious complications, identifying one-fourth of complicated cases.
The combination of these preoperative risk factors was significantly linked to extended intensive care unit and overall hospital length of stay.

Study Design

Type

Cohort (n=418)

Structured PICO

Do preoperative assessments predict in-hospital complications in adults undergoing elective craniotomy?

Population

418 consecutive adults undergoing elective craniotomy for any intracranial lesion, evaluated for preoperative predictors of in-hospital complications.

Exposure

Preoperative assessments including patient-related data, routine blood tests, ASA Physical Status Classification, and Helsinki ASA classification

Outcome

In-hospital mortality, in-hospital systemic or infectious complications, and in-hospital CNS deficitshard clinical

Simple preoperative assessments including age, CRP, and Helsinki ASA score can identify elective craniotomy patients at high risk for in-hospital complications and extended resource use.

Cite This Study

synapsesocial.com/papers/6a74bccca44b96c1f7dbe03b https://doi.org/10.3171/2014.11.jns141970

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

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