What question did this study set out to answer?

To examine the relationship between casual postprandial plasma glucose (cPPG) and HbA1c in type 2 diabetes and evaluate a clinical glucose cutoff for predicting elevated HbA1c levels.

February 1, 2004Diabetes CareOpen Access

Utility of Casual Postprandial Glucose Levels in Type 2 Diabetes Management

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To examine the relationship between casual postprandial plasma glucose (cPPG) and HbA1c in type 2 diabetes and evaluate a clinical glucose cutoff for predicting elevated HbA1c levels.
Analyzed paired casual postprandial plasma glucose (1–4 hours post-meal) and HbA1c levels collected during a single clinical encounter in 1,827 unique patients with type 2 diabetes.
Determined linear correlations between cPPG and HbA1c across the entire cohort and stratified across treatment subgroups (diet alone, oral hypoglycemic agents, or insulin).
Overall cPPG correlated significantly with HbA1c (r = 0.63, P < 0.001), with the highest correlation observed in diet-treated patients (r = 0.75, P < 0.001) compared to those taking oral agents (r = 0.64, P < 0.001) or insulin (r = 0.56, P < 0.001).
A cPPG cutoff >150 mg/dl predicted HbA1c ≥7.0% with 78% sensitivity, 62% specificity, and an 80% positive predictive value, and predicted HbA1c >6.5% with 74% sensitivity, 66% specificity, and an 88% positive predictive value.

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Implication

Cross-sectional study finds casual postprandial glucose correlates with HbA1c in type 2 diabetes, suggesting a 150 mg/dl cutoff can quickly identify inadequate glycemic control.

Cite This Study

El‐Kebbi et al. (2004) studied this question.

synapsesocial.com/papers/6a74bd056a5eb4b8f50924fd https://doi.org/10.2337/diacare.27.2.335

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Implication

Cross-sectional study finds casual postprandial glucose correlates with HbA1c in type 2 diabetes, suggesting a 150 mg/dl cutoff can quickly identify inadequate glycemic control.

Utility of Casual Postprandial Glucose Levels in Type 2 Diabetes Management

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Discussion

Implication

Cite This Study

Utility of Casual Postprandial Glucose Levels in Type 2 Diabetes Management

Key Points

Discussion

Implication

Cite This Study

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