Why the study?
Does aging attenuate the ventilatory and heart rate responses to hypoxia and hypercapnia in normal men?
Population
16 normal men free of cardiopulmonary disease and with no significant prior exposure to hypoxia.
Comparison
Isocapnic progressive hypoxia and hyperoxic… vs Comparison between young normal men and elderly…
Design
Cross-sectional
Authors
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Aging may heighten elderly men's hypoxia vulnerability; cross-sectional data leaves open causal mechanisms and clinical relevance.
Does aging attenuate the ventilatory and heart rate responses to hypoxia and hypercapnia in normal men?
Aging significantly attenuates both ventilatory and heart rate responses to hypoxia and hypercapnia, potentially increasing vulnerability to hypoxic disease states in the elderly.
Kronenberg et al. (1973) studied this question.
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