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August 1, 1979Annals of Internal Medicine

Clinical Indicators of Left Main Coronary Artery Disease in Unstable Angina

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Why the study?

Can clinical and noninvasive indicators reliably predict left main coronary artery disease in patients with unstable angina pectoris before coronary arteriography?

Population

200 consecutive catheterized patients with unstable angina pectoris

Design

Cohort

Authors

GPGary D. PlotnickUniversity of Maryland, BaltimoreHGH.Leon GreeneUniversity of Pittsburgh at GreensburgNCNathan H. CarlinerUniversity of Maryland, Baltimore

Discussion

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Implication

Noninvasive signs lack reliability for left main prediction in unstable angina; leaves open need for better predictors and arteriography confirmation.

Structured PICO

Can clinical and noninvasive indicators reliably predict left main coronary artery disease in patients with unstable angina pectoris before coronary arteriography?

P
Population
200 consecutive catheterized patients with unstable angina pectoris
I
Intervention
Clinical and noninvasive indicators (including crescendo angina pectoris, transient ST-segment depression, simultaneous anterior and inferior ST changes, and fluoroscopic calcification)
O
Outcome
Presence of left main coronary artery disease (≥50% lesion)surrogate

Clinical and noninvasive indicators cannot reliably predict the presence of left main coronary artery disease in patients with unstable angina, necessitating coronary arteriography for definitive diagnosis.

Limitations

  • Low sensitivity or low predictive value of clinical predictors

Cite This Study

Plotnick et al. (1979) studied this question.

synapsesocial.com/papers/6a74cbf5f1e99ff85ab1cd37https://doi.org/10.7326/0003-4819-91-2-149

Topics

Heart failureHFrEF treatment
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