Key result
Left bundle branch block (HR 2.80) and an abnormal Q wave (HR 2.21) were independent predictors of cardiovascular death in patients with end-stage hypertrophic cardiomyopathy.
Why the study?
Do electrocardiographic features such as LBBB and abnormal Q waves predict cardiovascular mortality in patients with end-stage hypertrophic cardiomyopathy?
Population
99 patients with end-stage hypertrophic cardiomyopathy enrolled from a total of 1844 consecutive HCM…
Design
Cohort
Follow-up
3.9 ± 3.0 years
Authors
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In patients with end-stage hypertrophic cardiomyopathy, the presence of left bundle branch block (LBBB) and abnormal Q waves on electrocardiography are independent predictors of cardiovascular mortality.
Cohort (n=99)
No
Do electrocardiographic features such as LBBB and abnormal Q waves predict cardiovascular mortality in patients with end-stage hypertrophic cardiomyopathy?
Hazard Ratio: 2.8 (95% CI 1.47–5.31)
p-value: p=0.002
In patients with end-stage hypertrophic cardiomyopathy, the presence of left bundle branch block (LBBB) and abnormal Q waves on electrocardiography are independent predictors of cardiovascular mortality.
Xiao et al. (2015) conducted a cohort in End-stage Hypertrophic Cardiomyopathy (n=99). Left bundle branch block (LBBB) vs. Absence of LBBB was evaluated on Cardiovascular death (HR 2.80, 95% CI 1.47-5.31, p=0.002). Left bundle branch block (HR 2.80) and an abnormal Q wave (HR 2.21) were independent predictors of cardiovascular death in patients with end-stage hypertrophic cardiomyopathy.
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