Key result
Iloprost treatment guided by duplex ultrasonography achieved complete revascularization after 10 days and subsequent regression of digital necrosis in a patient with thromboangiitis obliterans.
Why the study?
Does duplex ultrasonography-guided iloprost perfusion improve revascularization and reduce necrosis in a patient with thromboangiitis obliterans?
Case Report (n=1)
No
Does duplex ultrasonography-guided iloprost perfusion improve revascularization and reduce necrosis in a patient with thromboangiitis obliterans?
Duplex ultrasonography can be used to optimize iloprost dosing and duration in thromboangiitis obliterans, potentially reducing side effects and costs.
May inform individualized iloprost use in thromboangiitis obliterans; leaves open confirmation in prospective trials before practice change.
We present a 34-year-old patient with digital necrosis due to thromboangiitis obliterans. He was successfully treated with iloprost, a prostaglandin analogue. Duplex ultrasonography was performed during the perfusion of iloprost to optimize the doses and the treatment duration. A complete revascularization was observed after 10 days. Iloprost perfusions were stopped, and a slow regression of the necroses was observed in the subsequent days. With the use of duplex ultrasonography, unnecessary high doses of iloprost and long periods of treatment can be avoided reducing side effects and treatment costs.
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Noël et al. (2004) conducted a case report in Thromboangiitis obliterans with digital necrosis (n=1). Iloprost guided by duplex ultrasonography was evaluated on Revascularization and regression of necroses. Iloprost treatment guided by duplex ultrasonography achieved complete revascularization after 10 days and subsequent regression of digital necrosis in a patient with thromboangiitis obliterans.
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