Proteins on the move: The techniques of organic synthesis and molecular biology have been used to develop biological systems amenable to dynamic characterization by spectroscopic techniques (see picture). This review focuses on three novel systems designed to study tautomerization dynamics in DNA, the role of protein dynamics in function and folding, and molecular recognition within the immune system. These studies illustrate our efforts to understand biomolecule dynamics and to test whether nature has evolved biomolecules with specific dynamic properties tailored to perform specific biological functions.
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Floyd E. Romesberg (2003) studied this question.
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