Key result
Changes in blood pressure over 4 years were not significantly associated with cognitive status overall, though a 10 mmHg decrease in systolic blood pressure was associated with higher cognitive scores in men with medically controlled hypertension (β = -0.44).
Why the study?
Are 4-year changes in systolic and diastolic blood pressure associated with cognitive status in older adults?
Population
854 participants of a population-based German sample, aged 60-87 years, excluding those with cardiovascular…
Design
Cohort
Follow-up
mean 4 years
Authors
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BP changes over time show no broad cognitive link, advising against practice changes; the controlled-HTN male subgroup signal is hypothesis-generating.
Cohort (n=854)
Are 4-year changes in systolic and diastolic blood pressure associated with cognitive status in older adults?
Mean Difference: -0.44 (95% CI -0.92–-0.03)
Decreases in systolic blood pressure over 4 years are weakly associated with better cognitive scores in older men with medically controlled hypertension.
Lacruz et al. (2016) conducted a cohort in Cognitive status (n=854). Changes in systolic and diastolic blood pressure vs. No change in blood pressure was evaluated on Cognitive status (MMSE score) (β = -0.44, 95% CI -0.92 to -0.03). Changes in blood pressure over 4 years were not significantly associated with cognitive status overall, though a 10 mmHg decrease in systolic blood pressure was associated with higher cognitive scores in men with medically controlled hypertension (β = -0.44).
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