What is the clinical evidence from this study?

Study design: Cross-Sectional. Population: Obesity (n=30). Intervention: Obesity vs. Eutrophic (normal weight). Primary outcome: Correlation between biochemical parameters, serum proinflammatory cytokines and adipokines.

January 31, 2018Endocrine Metabolic & Immune Disorders - Drug Targets

Obesity in young adults was associated with higher levels of proinflammatory cytokines and lower adiponectin compared to eutrophic controls.

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Population

30 young adults divided by BMI into eutrophic (n=10), overweight (n=10), and obese (n=10) groups

Design

Cross-sectional

Key result

Obesity in young adults was associated with higher levels of proinflammatory cytokines and lower adiponectin compared to eutrophic controls.

Authors

MBMaraísa Delmut Borges EFEduardo Luzía França MFMahmi Fujimori

Discussion

Member takes

Overview

Does not warrant practice change; hypothesis-generating for cytokine-adipokine links in early obesity.

Study Design

Type

Cross-Sectional (n=30)

Structured PICO

Population

30 young adults categorized by BMI into eutrophic, overweight, and obese groups to evaluate metabolic and inflammatory profiles.

Outcome

Correlation between biochemical parameters, serum proinflammatory cytokines (IL-8, TNF-α, IL-1β, IL-6), and adipokines (leptin, adiponectin)surrogate

Obesity is associated with an altered lipid and glycemic profile and a shift towards a proinflammatory state characterized by increased proinflammatory cytokines and decreased anti-inflammatory adipokines.

Cite This Study

Borges et al. (2018) conducted a cross-sectional in Obesity (n=30). Obesity vs. Eutrophic (normal weight) was evaluated on Correlation between biochemical parameters, serum proinflammatory cytokines and adipokines. Obesity in young adults was associated with higher levels of proinflammatory cytokines and lower adiponectin compared to eutrophic controls.

synapsesocial.com/papers/6a74fa5aa44b96c1f7dbe9cf https://doi.org/10.2174/1871530318666180131094733

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January 31, 2018Endocrine Metabolic & Immune Disorders - Drug Targets

Obesity in young adults was associated with higher levels of proinflammatory cytokines and lower adiponectin compared to eutrophic controls.

View Full Paper

Ask AI

Bookmark

Population

30 young adults divided by BMI into eutrophic (n=10), overweight (n=10), and obese (n=10) groups

Design

Cross-sectional

Key result

Obesity in young adults was associated with higher levels of proinflammatory cytokines and lower adiponectin compared to eutrophic controls.

Authors

MBMaraísa Delmut Borges EFEduardo Luzía França MFMahmi Fujimori

Discussion

Member takes

Overview

Does not warrant practice change; hypothesis-generating for cytokine-adipokine links in early obesity.

Study Design

Type

Cross-Sectional (n=30)

Structured PICO

Population

30 young adults categorized by BMI into eutrophic, overweight, and obese groups to evaluate metabolic and inflammatory profiles.

Outcome

Correlation between biochemical parameters, serum proinflammatory cytokines (IL-8, TNF-α, IL-1β, IL-6), and adipokines (leptin, adiponectin)surrogate

Cite This Study

synapsesocial.com/papers/6a74fa5aa44b96c1f7dbe9cf https://doi.org/10.2174/1871530318666180131094733

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

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