Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
November 2, 2022Journal of Personalized MedicineOpen Access

Adipokines, Metabolic Hormones and Their Associations with Abdominal Obesity against a Background of Hyper-LDL-C in Young People

View Full Paper
Ask AI
Bookmark
Share

Why the study?

The study was designed to search for possible associations between various adipokines or cytokines, elevated blood levels of LDL-C, and abdominal obesity in people under 45 years.

Population

158 people under 45 years with serum LDL-C levels of ≥4.2 mmol/L

Comparison

Abdominal obesity vs no abdominal obesity

Design

Population-based cross-sectional study

Authors

YRYu. I. RaginoYPYana V. PolonskayaASA. N. Spiridonov

Discussion

Loading...

Member takes

Overview

Associations in young adults with abdominal obesity and high LDL-C are hypothesis-generating; leaves open causal validation before any clinical application.

Structured PICO

P
Population
158 young people (under 45 years), 87 men and 71 women, from Novosibirsk, with serum LDL-C levels of ≥4.2 mmol/L. 50% had abdominal obesity.
O
Outcome
Association of adipokines and inflammatory markers with the presence of abdominal obesitysurrogate

In young adults with elevated LDL-C, specific adipokines such as leptin and lipocalin-2 are significantly associated with abdominal obesity, highlighting potential metabolic pathways linking adiposity and atherogenic risk.

Cite This Study

Ragino et al. (2022) studied this question.

synapsesocial.com/papers/6a8a7b2706e1858e55de9014https://doi.org/10.3390/jpm12111823
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Associations of adupocutokine and metaboliv hormone level in young people aged 25-44 years with type 2 diabetes mellitus and abdominal obesity2024 · 1 citations
  2. 2Relationship between Proinflammatory Cytokines/Chemokines and Adipokines in Serum of Young Adults with Obesity2018 · 70 citations
  3. 3Associations of visceral adipose tissue adipokines with metabolic disorders in abdominal obesity2025
  4. 4Associations of adipocytokines and kidney function in young people with abdominal obesity2024 · 1 citations
  5. 5The Adipokine Profile and the Cardiometabolic Risk in Non-Obese Young Adults2019 · 12 citations