Why the study?
Does diuretic therapy affect the plasma lipid profile in hypertensive patients?
Does diuretic therapy affect the plasma lipid profile in hypertensive patients?
High-dose thiazides and loop diuretics can adversely affect lipid profiles, whereas indapamide and spironolactone appear to be lipid-neutral.
No takes yet. Share an insight, caveat, or question.
Diuretic choice in hypertension warrants lipid consideration; supports neutral agents like indapamide but leaves optimal selection open pending RCTs.
Weidmann et al. (1992) studied this question.
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