Key result
Quantitative ultrasound parameters demonstrated steatosis grading accuracies of 61.7% and 68.3%, compared to 51.7% for conventional ultrasound and 76.7% for MRI-estimated PDFF.
Why the study?
Does quantitative ultrasound improve diagnostic accuracy for predicting hepatic steatosis grade compared to conventional ultrasound in adults with NAFLD?
Population
61 adults with histology-confirmed nonalcoholic fatty liver disease (NAFLD)
Comparison
Quantitative ultrasound parameters vs Conventional ultrasound and MRI-estimated proton…
Design
Cross-sectional, QUS parameters estimated by two analysts independently; CUS…
Authors
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Quantitative ultrasound may improve steatosis grading over conventional ultrasound but trails MRI; leaves open clinical adoption pending validation.
Observational (n=61)
Does quantitative ultrasound improve diagnostic accuracy for predicting hepatic steatosis grade compared to conventional ultrasound in adults with NAFLD?
Absolute Event Rate: 68.3% vs 51.7%
Quantitative ultrasound parameters may provide higher accuracy and interobserver agreement than conventional ultrasound for predicting hepatic steatosis grade in NAFLD.
Paige et al. (2017) conducted an observational in Nonalcoholic fatty liver disease (NAFLD) (n=61). Quantitative ultrasound (QUS) vs. Conventional ultrasound (CUS) and MRI-estimated PDFF was evaluated on Accuracy to predict histology-confirmed steatosis grade. Quantitative ultrasound parameters demonstrated steatosis grading accuracies of 61.7% and 68.3%, compared to 51.7% for conventional ultrasound and 76.7% for MRI-estimated PDFF.
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