Why the study?
Does oxidized LDL potentiate microvascular dysfunction and leukocyte-endothelial cell adhesion during ischemia-reperfusion or chronic hypertension in rat mesentery?
Does oxidized LDL potentiate microvascular dysfunction and leukocyte-endothelial cell adhesion during ischemia-reperfusion or chronic hypertension in rat mesentery?
Oxidized LDL acts synergistically with ischemia-reperfusion to promote leukocyte recruitment in postcapillary venules, but does not elicit a more intense inflammatory response in hypertensive compared to normotensive animals.
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Oxidized LDL may synergize with I/R to promote rat venular leukocyte recruitment without hypertension exacerbation; leaves open clinical translation.
Liao et al. (1996) studied this question.
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