Population
116 normal male subjects free of any cardiovascular or pulmonary disease, initial age 23 to 76 years.
Design
Cohort, Films evaluated by at least two experienced radiologists with all…
Follow-up
mean 17.3 years
Authors
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May prompt caution against overdiagnosing COPD on aging chest X-rays; supports age-specific norms but leaves open prospective validation.
Normal aging is associated with specific chest X-ray changes such as aortic root dilatation and pulmonary artery enlargement, which can mimic pathological conditions like COPD.
Ensor et al. (1981) studied this question.
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