Why the study?
Does once-daily timolol reduce left ventricular mass index in patients with mild to moderate hypertension?
Population
46 patients with mild to moderate hypertension
Design
Cohort
Follow-up
16 weeks
Authors
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May support ambulatory BP monitoring for LVH risk stratification; small timolol cohort leaves open its role in regression pending RCTs.
Does once-daily timolol reduce left ventricular mass index in patients with mild to moderate hypertension?
Ambulatory systolic blood pressure correlates strongly with left ventricular mass index, which can be reduced with timolol therapy.
Rowlands et al. (1981) studied this question.