What question did this study set out to answer?

To describe hemodynamic, metabolic, and ventilatory responses during cardiopulmonary exercise testing in adults with congenital heart disease.

January 1, 2018International Journal of Cardiovascular SciencesOpen Access

Hemodynamic, Metabolic and Ventilatory Responses to Exercise in Adults with Congenital Heart Disease

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Population

31 adults with congenital acyanotic or cyanotic heart disease, treated clinically, surgically or…

Design

Cross-sectional

Authors

PNPablo Marino Corrêa NascimentoUniversidade Federal Fluminense DKDaniel Arkader KopilerInstituto Nacional de Cardiologia FSFernando César de Castro e SouzaInstituto Nacional de Cardiologia

Discussion

Member takes

Implication

May support CPET for ACHD assessment; leaves open prospective validation before clinical adoption.

Key Points

To describe hemodynamic, metabolic, and ventilatory responses during cardiopulmonary exercise testing in adults with congenital heart disease.
Observational cross-sectional study of 31 adults with acyanotic or cyanotic congenital heart disease treated clinically, surgically, or percutaneously.
Patients underwent cardiopulmonary exercise testing to assess gas exchange, functional capacity, and cardiovascular metrics.
Peak oxygen consumption (VO2) was 44.86 ± 18.01% of predicted, and VO2 at the anaerobic threshold was 36.92 ± 12.93% of predicted maximal VO2 in patients aged 35.7 ± 14.2 years.
The oxygen uptake efficiency slope was 1.49 ± 0.89 (61.43 ± 26.63% of predicted), mean oxygen pulse reached 58.90 ± 22.24% of predicted, and exercise induced a systolic arterial pressure rise of 31.42 ± 21.60 mmHg.

Structured PICO

Population

31 adults with congenital acyanotic or cyanotic heart disease, treated clinically, surgically or percutaneously, referred for cardiopulmonary exercise test, mean age 35.7 years.

Outcome

Hemodynamic, metabolic and ventilatory parameters in response to exercise (including VO2, OUES, oxygen pulse, and systolic arterial pressure increment)surrogate

Adults with congenital heart disease exhibit reduced aerobic capacity, ventilatory inefficiency, and limited inotropic response during exercise, similar to patients with heart failure.

Cite This Study

Nascimento et al. (2018) studied this question.

synapsesocial.com/papers/6a7552bef1e99ff85ab1e1e2 https://doi.org/10.5935/2359-4802.20180073

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