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This interview highlights basic science research on the genetic regulation of cardiomyocyte polyploidy during development in mice.
Cardiomyocytes are polyploid, but how this polyploidy is established during development is unclear. In a new paper in Development, Samantha Swift and colleagues reveal variation in cardiomyocyte polyploidy between mouse strains and identify candidates that regulate this phenotype. We caught up with first author, Samantha Swift, and corresponding author, Michaela Patterson (Assistant Professor at the Medical College of Wisconsin, USA), to learn more about their research.
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