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August 17, 2015Journal of the American Geriatrics Society

Age‐ and Functional Status–Dependent Association Between Blood Pressure and Cognition: The Milan Geriatrics 75+ Cohort Study

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Why the study?

Is higher blood pressure associated with better cognitive function in older outpatients aged 75 and older?

Population

1,540 older outpatients aged 75 and older from the hospital-based Milan Geriatrics 75+ Cohort Study

Comparison

Higher blood pressure vs Lower blood pressure

Design

Cross-sectional

Authors

GOGiulia OgliariBSBehnam SabayanDMDaniela Mari

Discussion

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Overview

Higher BP linked to better cognition in frail oldest-old; hypothesis-generating, should not yet alter BP targets.

Structured PICO

Is higher blood pressure associated with better cognitive function in older outpatients aged 75 and older?

P
Population
1,540 older outpatients aged 75 and older from the hospital-based Milan Geriatrics 75+ Cohort Study
I
Intervention
Higher blood pressure (systolic, diastolic, pulse pressure, and mean arterial pressure)
C
Comparator
Lower blood pressure
O
Outcome
Cognitive function assessed by Mini-Mental State Examination (MMSE) scoresurrogate

Higher blood pressure is associated with better cognitive function in the oldest old and those with impaired functional status, suggesting a potential need for individualized BP targets in frail older adults.

Cite This Study

Ogliari et al. (2015) studied this question.

synapsesocial.com/papers/6a75559cfc5fd65369f5455chttps://doi.org/10.1111/jgs.13616
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