Population
CATH.a neuronal cell culture
Comparison
Angiotensin II exposure, with or without GSK-3β… vs Control cells without Angiotensin II exposure or…
Design
Preclinical
Authors
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GSK-3β inhibition may target hypertension neuroinflammation; leaves open translation from animal models to clinical use.
Angiotensin II induces a pro-inflammatory cytokine imbalance in neuronal cells via GSK-3β activation, suggesting GSK-3β as a potential therapeutic target for hypertension-associated neuroinflammation.
Agarwal et al. (2013) studied this question.
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