Why the study?
Does ramipril modulate right ventricular hypertrophy in a rat model of pulmonary artery stenosis?
Does ramipril modulate right ventricular hypertrophy in a rat model of pulmonary artery stenosis?
In a rat model of pulmonary artery stenosis, ACE inhibition with ramipril attenuated right ventricular myocyte hypertrophy at the cellular level without affecting right ventricular systolic pressure or overall right ventricular weight.
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May attenuate cellular RV hypertrophy without hemodynamic effects; hypothesis-generating for ACE inhibition in pulmonary hypertension.
Heinz‐Gerd Zimmer (1992) studied this question.
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