Population
Calcium-saturated cardiac troponin C bound to the NH2-terminal domain of cardiac troponin I- and cardiac…
Comparison
Binding of cardiac troponin I-(1-80) vs Free cardiac troponin C and cardiac troponin C…
Design
Preclinical
Authors
Loading...
Alters troponin C domain dynamics in vitro; hypothesis-generating for contractile regulation, pending intact-system validation.
The nonphosphorylated cardiac-specific NH2 terminus of cardiac troponin I interacts with the NH2-terminal domain of cardiac troponin C, altering its conformational dynamics.
Gaponenko et al. (1999) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: