Population
Bovine cardiac troponin C (cTnC)
Comparison
Calcium binding (Ca2+) vs Apo-cTnC (calcium-free state)
Design
Preclinical
Authors
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Bovine troponin C calcium-binding data remain preliminary; leaves open translation to human cardiac regulation or therapies.
Calcium binding to bovine cardiac troponin C induces significant structural changes, particularly in the environments of tyrosines-10 and -150, revealing structural similarities with calmodulin.
Hincke et al. (1981) studied this question.
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