Why the study?
Two-dimensional speckle-tracking echocardiography allows assessment of regional myocardial function, but its use to assess left ventricular deformation in coarctation of the aorta needed evaluation.
Does 2D-STE detect differences in left ventricular deformation between children with coarctation of the aorta and healthy controls?
Does 2D-STE detect differences in left ventricular deformation between children with coarctation of the aorta and healthy controls?
2D-STE reveals that while overall left ventricular strain is preserved in children with coarctation of the aorta, it is reduced in those with concurrent hypertension.
Background/aim: Two-dimensional speckle-tracking echocardiography (2D-STE) is a novel method that allows the assessment of regional myocardial function. The aim of our study was to use 2D-STE to assess left ventricular deformation in patients with coarctation of the aorta (CoA). Methods: In this prospective study, patients with CoA (n = 42) and healthy controls (n = 39) were recruited. Children with CoA who visited the outpatient clinic between 2013 and 2014 were included. The data were compared with those obtained from the sex- and age-matched controls. Results: The mean age of the patients was 5.8 ± 4.5 years. Global longitidinal strain based on all three apical views and total global strain values did not appear to be different between the patient and the control group (p = 0.59, p = 0.51, p = 0.15, p = 0.38). Hypertension was detected in 14 (33.3%) patients with CoA. There were significant differences between the global longitudinal strain values of the normotensive CoA subgroup and the hypertensive CoA subgroup (p < .05). Conclusions: In our study, we found that 2D-STE total strain analysis of patients with CoA was not different from comparative healthy controls. However, we determined that 2D-STE parameters were lower in the hypertensive CoA subgroup compared to the normotensive CoA subgroup.
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Demircan et al. (2020) studied this question.
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