Why the study?
Aortic coarctation is safely repaired in infancy, but mortality and morbidity remain increased in later life, prompting investigation into LV myocardial deformation and hemodynamic forces in asymptomatic repaired patients.
Are LV myocardial strain and hemodynamic forces altered in asymptomatic patients with repaired aortic coarctation and preserved LVEF compared to hypertensive patients and healthy controls?
Are LV myocardial strain and hemodynamic forces altered in asymptomatic patients with repaired aortic coarctation and preserved LVEF compared to hypertensive patients and healthy controls?
In patients with repaired aortic coarctation and preserved LVEF, subclinical LV dysfunction detected by impaired myocardial strain and hemodynamic forces is associated with future heart failure hospitalization.
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Impaired strain and forces may flag HF risk in repaired CoA despite preserved LVEF; hypothesis-generating for deformation imaging in congenital cohorts.
Faganello et al. (2024) studied this question.
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