What question did this study set out to answer?

To determine the nationwide incidence and subtype-specific survival rates of non-hereditary amyloidosis in Sweden.

November 13, 2012BMC Public HealthOpen Access

Incidence and survival in non-hereditary amyloidosis in Sweden

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To determine the nationwide incidence and subtype-specific survival rates of non-hereditary amyloidosis in Sweden.
Extracted non-hereditary amyloidosis patient data (N=949) from the Swedish Hospital Discharge and Outpatients Registers between 2001 and 2008.
Estimated secondary systemic and immunoglobulin light chain (AL) amyloidosis rates by cross-referencing death causes with rheumatoid arthritis and myeloma.
The overall incidence of non-hereditary amyloidosis was 8.29 per million person-years, with diagnosis frequency peaking in individuals over 65 years of age.
Median survival was 6 years for organ-limited disease, 4 years for secondary systemic amyloidosis, and 3 years for unspecified/other forms presumed to be AL amyloidosis.
Corrected incidence estimates after accounting for diagnostic coding limitations were approximately 3.2 per million for AL amyloidosis and 2.0 per million for secondary systemic amyloidosis.

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Implication

Population-based cohort study reveals an incidence of 8.29 per million for non-hereditary amyloidosis in Sweden, indicating substantial undercoding of specific systemic subtypes.

Cite This Study

Hemminki et al. (2012) studied this question.

synapsesocial.com/papers/6a7564071646b2abe5036ba9 https://doi.org/10.1186/1471-2458-12-974

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Implication

Population-based cohort study reveals an incidence of 8.29 per million for non-hereditary amyloidosis in Sweden, indicating substantial undercoding of specific systemic subtypes.

Incidence and survival in non-hereditary amyloidosis in Sweden

Key Points

Discussion

Implication

Cite This Study

Incidence and survival in non-hereditary amyloidosis in Sweden

Key Points

Discussion

Implication

Cite This Study

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