Why the study?
Cirrhotic cardiomyopathy involves altered diastolic relaxation and impaired contractile reactivity to stress, prompting evaluation of left ventricular systolic and diastolic performance via tissue Doppler in liver cirrhosis.
Does liver cirrhosis severity correlate with impaired left ventricular systolic and diastolic function as assessed by tissue Doppler imaging?
Does liver cirrhosis severity correlate with impaired left ventricular systolic and diastolic function as assessed by tissue Doppler imaging?
Liver cirrhosis is associated with impaired left ventricular systolic and diastolic function, which worsens with the severity of hepatic decompensation.
May identify subclinical LV dysfunction in cirrhosis; leaves open whether tissue Doppler improves risk stratification or outcomes.
Background: Chronic cardiac disease known as cirrhotic cardiomyopathy dysfunction in cirrhotic patients characterised by altered diastolic relaxation and/or impaired contractile reactivity to stress in the absence of other recognised cardiac diseases.. Aim and objectives: The purpose of the study was to evaluate tissue Doppler the left ventricle's systolic and diastolic characteristics performance in patients with liver cirrhosis. Subjects and methods: Al-Hussien Hospital, Al-Azhar University, did this cross-sectional case-control study, The study included 75 patients with liver cirrhosis and 25 healthy participants. There were four groups created from the study populations: 25 healthy volunteers make up the control group. Patients in Group 1 have Child A liver cirrhosis, while those in Group 2 have Child B cirrhosis. Group 2., Group 3, which consists of patients with Child C liver cirrhosis. Participants conducted transthoracic echocardiography, tissue collection, and left lateral decubitus for assessment. We followed ASE's Doppler echocardiography guidelines. LV systole function. Results: A statistically significant higher mean value in patients group compared to control group according to MPI PWD, MPI TDI, MV E/É ratio, DT (ms) and IVRT (ms) with p-value; The average values of the EF by Simpson, Average S wave, and EF by M mode all differed significantly. when comparing the sick group to the control group., and MV E/A ratio was seen. A p-value of 0.05 was used to determine this difference. Conclusion: Compared to the control group, patients with liver cirrhosis exhibited significantly worse left ventricular systolic and diastolic functioning, and the decompensated patients showed a greater difference than the compensated patients.
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Alnadry et al. (2023) studied this question.
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