Why the study?
Does metoprolol compared to captopril improve heart rate variability in patients with mild to moderate heart failure due to idiopathic dilated cardiomyopathy?
Does metoprolol compared to captopril improve heart rate variability in patients with mild to moderate heart failure due to idiopathic dilated cardiomyopathy?
Both metoprolol and captopril increase heart rate variability in patients with idiopathic dilated cardiomyopathy, with metoprolol demonstrating a more pronounced effect across both time and frequency domains.
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Favors metoprolol over captopril for autonomic modulation in mild HF; extends comparative RCT data on HRV in dilated cardiomyopathy.
Jansson et al. (1999) studied this question.
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