Why the study?
The haemodynamic mechanisms of vasovagal syncope remain poorly defined, and data on age-related differences are limited and sometimes contradictory.
Do haemodynamic adaptation patterns during head-up tilt testing differ between paediatric and adult patients with recurrent reflex syncope?
Do haemodynamic adaptation patterns during head-up tilt testing differ between paediatric and adult patients with recurrent reflex syncope?
Paediatric patients with reflex syncope exhibit more abrupt decreases in cardiac output and total peripheral resistance, alongside higher heart rate responses during orthostatic stress compared to adults.
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Age-specific HUT patterns may inform tailored syncope evaluation; leaves open need for prospective validation before practice change.
Laranjo et al. (2025) studied this question.
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