Why the study?
Does human GH treatment improve growth rate in short children with low spontaneous GH secretion, and does it correlate with IGF-I and IGF-II responses?
Population
31 children who were short but not GH deficient, with normal serum GH responses to provocative tests and low…
Design
Cohort
Follow-up
1 year
Authors
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May support early IGF monitoring to predict GH response in short children; leaves open need for randomized confirmation.
Does human GH treatment improve growth rate in short children with low spontaneous GH secretion, and does it correlate with IGF-I and IGF-II responses?
Human GH treatment increases the growth rate in short children with low spontaneous GH secretion, with the response strongly correlating with early increases in serum IGF-I and IGF-II levels.
Albertsson‐Wikland et al. (1987) studied this question.
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