Why the study?
Does combined ergotamine and synthetic oxytocin increase plasma oxytocin concentration in women during the third stage of labour?
Population
25 women in the late second stage and throughout the third stage of labour
Comparison
Combined ergotamine and synthetic oxytocin… vs No treatment
Design
Cohort
Follow-up
throughout the third stage of labour
Authors
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Routine oxytocin may ensure adequate levels in third-stage labour where endogenous rises vary; leaves open need for RCTs to guide targeted use.
Does combined ergotamine and synthetic oxytocin increase plasma oxytocin concentration in women during the third stage of labour?
Intramuscular oxytocin should be given routinely during the third stage of labour as it is impossible to predict which women will have a sufficient endogenous oxytocin rise to prevent complications.
Thornton et al. (1988) studied this question.
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