Key result
An additional 2 U of oxytocin immediately after birth in women with heart disease was associated with significantly lower blood loss (505 vs 849 mL) and no adverse cardiac consequences.
Why the study?
Does an additional 2 U of oxytocin safely reduce blood loss and postpartum haemorrhage in women with heart disease during the third stage of labour?
Cohort (n=59)
No
Does an additional 2 U of oxytocin safely reduce blood loss and postpartum haemorrhage in women with heart disease during the third stage of labour?
Absolute Event Rate: 505% vs 849%
An additional 2 U of oxytocin immediately after birth in women with heart disease safely reduces blood loss without adverse cardiac consequences.
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Additional oxytocin may safely reduce blood loss in women with heart disease at delivery; observational data leaves open need for randomized confirmation.
Cauldwell et al. (2016) conducted a cohort in Heart disease (n=59). Additional 2 U of oxytocin vs. Standard low-dose oxytocin infusion (10 U in 500 mL at 36 mL/hour for 4 hours) was evaluated on Total blood loss at 12 hours. An additional 2 U of oxytocin immediately after birth in women with heart disease was associated with significantly lower blood loss (505 vs 849 mL) and no adverse cardiac consequences.
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