October 1, 1993Journal of Biological ChemistryOpen Access

Skelemin, a cytoskeletal M-disc periphery protein, contains motifs of adhesion/recognition and intermediate filament proteins.

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Population

Mouse muscle cDNA / striated muscle model

Design

Preclinical

Authors

MPMaureen G. PriceBaylor College of Medicine RGRichard H. GomerTexas A&M University

Discussion

Member takes

Implication

Preclinical finding in animal muscle; leaves open skelemin's role in human cardiac cytoskeletal linkage.

Structured PICO

Population

Mouse muscle cDNA / striated muscle model

Intervention

Immunoscreening and molecular characterization of skelemin

Outcome

Identification and characterization of skelemin cDNA and protein motifs

Skelemin is identified as a unique myosin-associated protein with motifs that suggest it links myofibrils to the intermediate filament cytoskeleton in striated muscle.

Cite This Study

Price et al. (1993) studied this question.

synapsesocial.com/papers/6a75747ef2cd31a1fadc130b https://doi.org/10.1016/s0021-9258(20)80613-9

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Skelemin, a cytoskeletal M-disc periphery protein, contains motifs of adhesion/recognition and intermediate filament proteins.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Skelemin, a cytoskeletal M-disc periphery protein, contains motifs of adhesion/recognition and intermediate filament proteins.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider