Why the study?
Does GATA3 immunohistochemical staining differentiate pheochromocytoma from adrenal cortical carcinoma in adrenal lesions?
Does GATA3 immunohistochemical staining differentiate pheochromocytoma from adrenal cortical carcinoma in adrenal lesions?
GATA3 immunohistochemistry may be useful as part of a panel to differentiate pheochromocytoma from adrenal cortical carcinoma, though expression in metastatic pulmonary adenocarcinoma can confound diagnosis.
GATA3 positivity may favor pheochromocytoma over cortical carcinoma; leaves open its diagnostic role pending validation.
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Perrino et al. (2017) studied this question.
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