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November 22, 2011Cardiovascular DiabetologyOpen Access

Association of circulating omentin-1 level with arterial stiffness and carotid plaque in type 2 diabetes

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Why the study?

Is circulating omentin-1 level associated with arterial stiffness and carotid plaque in patients with type 2 diabetes?

Population

90 participants: 60 with type 2 diabetes and 30 with normal glucose tolerance.

Design

Cross-sectional

Authors

HYHye Jin YooKorea University Medical Center SHSoon Young HwangKorea University HHHo Cheol HongMalacca General Hospital

Discussion

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Implication

Omentin-1 levels were associated with carotid plaque in T2D; leaves open whether measurement aids risk stratification or warrants intervention.

Structured PICO

Is circulating omentin-1 level associated with arterial stiffness and carotid plaque in patients with type 2 diabetes?

P

Population

90 participants: 60 with type 2 diabetes (with or without carotid plaque) and 30 with normal glucose tolerance.

I

Intervention

Measurement of serum omentin-1 levels

O

Outcome

Arterial stiffness (assessed by brachial ankle pulse wave velocity) and presence of carotid plaque (assessed by carotid intima-media thickness)surrogate

Lower circulating omentin-1 levels are independently associated with increased arterial stiffness and the presence of carotid plaque in patients with type 2 diabetes.

Cite This Study

Yoo et al. (2011) studied this question.

synapsesocial.com/papers/6a7579d8f2cd31a1fadc14e8 https://doi.org/10.1186/1475-2840-10-103

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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Omentin Plasma Levels and Gene Expression Are Decreased in Obesity2007 · 773 citations
2Serum Adipocyte Fatty Acid-Binding Protein Is Associated Independently with Vascular Inflammation: Analysis with<sup>18</sup>F-Fluorodeoxyglucose Positron Emission Tomography2010 · 49 citations
3Carotid Plaque, Intima Media Thickness, Cardiovascular Risk Factors, and Prevalent Cardiovascular Disease in Men and Women1999 · 775 citations
4Increased arterial stiffness in healthy subjects with high-normal glucose levels and in subjects with pre-diabetes2011 · 128 citations
5A Simple Oscillometric Technique for Determining New Indices of Arterial Distensibility.2002 · 122 citations