Why the study?
Preoperative pulmonary hypertension affects prognosis after surgical mitral valve intervention, prompting a review of the hemodynamic and clinical effects of MitraClip in severe mitral regurgitation and pulmonary hypertension.
Does transcatheter mitral valve repair with MitraClip improve haemodynamic and clinical outcomes in patients with severe mitral regurgitation and pulmonary hypertension?
Does transcatheter mitral valve repair with MitraClip improve haemodynamic and clinical outcomes in patients with severe mitral regurgitation and pulmonary hypertension?
This review summarizes the available literature on the hemodynamic and clinical effects of MitraClip in high-surgical-risk patients with severe mitral regurgitation and concurrent pulmonary hypertension.
PH portends worse prognosis after MitraClip; leaves open whether PH severity should guide patient selection.
Transcatheter mitral valve repair with MitraClip has emerged as a possible therapeutic option for patients with severe mitral regurgitation (MR) with high risk for surgical valve repair. MitraClip intervention has demonstrated to improve haemodynamics and clinical outcomes in selected patients in observational and randomized studies. Preoperative pulmonary hypertension (PH) is known to affect prognosis in patients undergoing surgical mitral valve intervention. The aim of the present review is to discuss the available literature focused on the haemodynamic and clinical effects of MitraClip in patients with severe MR and PH.
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Mandurino‐Mirizzi et al. (2021) studied this question.
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