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Highlights a new study demonstrating that HDL-associated lysophospholipids stimulate antiatherogenic nitric oxide production by the vascular endothelium.
Circulating levels of HDL cholesterol are inversely related to the risk of atherosclerosis, and therapeutic increases in HDL reduce the incidence of cardiovascular events. A new study shows that HDL-associated lysophospholipids stimulate the production of the potent antiatherogenic signaling molecule NO by the vascular endothelium.
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Shaul et al. (2004) studied this question.
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