Population
HeLa cells
Comparison
Adenovirus infection vs Uninfected HeLa cells
Design
Preclinical
Follow-up
2 to 24 hours after infection
Authors
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snRNP redistribution may support adenovirus late gene expression in animal models; leaves open human relevance and therapeutic targeting.
Adenovirus infection alters the nuclear organization of splicing snRNPs, concentrating them in interchromatin granule clusters during late gene expression.
Bridge et al. (1993) studied this question.
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