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September 15, 2009Quality of Life ResearchOpen Access

Measuring health-related quality of life in population-based studies of coronary heart disease: comparing six generic indexes and a disease-specific proxy score

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Why the study?

Do generic HRQoL indexes capture differences in quality of life among CHD patients similarly to a disease-specific proxy score?

Population

3,833 U.S. adults aged 35-89 from a nationally representative sample, plus 154 patients from heart failure…

Comparison

Administration of six generic HRQoL indexes and… vs Comparison between generic indexes and the…

Design

Cross-sectional

Authors

NGNoelle GarsterMedical College of WisconsinMPMari PaltaUniversity of Wisconsin–MadisonNSNancy K. SweitzerHeart Failure & Transplant

Discussion

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Implication

Generic indexes detect CHD QoL differences comparably to proxies; supports their use in cross-sectional research but leaves longitudinal validation open.

Structured PICO

Do generic HRQoL indexes capture differences in quality of life among CHD patients similarly to a disease-specific proxy score?

P
Population
3,833 U.S. adults aged 35-89 from a nationally representative sample (3,350 without CHD, 265 with CHD not taking chest pain medication, 218 with CHD taking chest pain medication), plus 154 patients from heart failure clinics.
I
Intervention
Administration of six generic HRQoL indexes (EQ-5D, QWB-SA, HUI2, HUI3, SF-36v2, HALex) and a disease-specific proxy score.
C
Comparator
Comparison between generic indexes and the disease-specific proxy score across different CHD severity groups.
O
Outcome
Differences in HRQoL scores between CHD groups, with and without adjustment for demographic variables and comorbidities.patient reported

Generic HRQoL indexes are as effective as disease-specific proxy scores in capturing quality of life differences in population-based studies of coronary heart disease.

Cite This Study

Garster et al. (2009) studied this question.

synapsesocial.com/papers/6a75890a12165deef3dd7de7https://doi.org/10.1007/s11136-009-9533-8
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