What question did this study set out to answer?

To evaluate the incidence, etiology, clinical manifestations, and associated mortality of hyponatraemia among geriatric department in-patients.

January 1, 1983Age and Ageing

Hyponatraemia in the Elderly

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Authors

SSSridhar SunderamUniversity of Kentucky GMG. D. MankikarBrighton General Hospital

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Implication

Observational study reveals high rates of drug-induced hyponatraemia and doubled mortality in geriatric in-patients, highlighting the risks of diuretic therapy.

Key Points

To evaluate the incidence, etiology, clinical manifestations, and associated mortality of hyponatraemia among geriatric department in-patients.
Conducted an observational study of in-patients admitted to a Geriatric Department over a 10-month period.
Identified hyponatraemia defined by plasma sodium levels < 130 mmol/l and severe cases defined as < 125 mmol/l.
Hyponatraemia occurred in 11.3% of patients (77 individuals), with 4.5% (31 individuals) experiencing severe hyponatraemia below 125 mmol/l.
Iatrogenic factors caused 73% of cases via diuretic or intravenous fluid therapy, with the hydrochlorothiazide/amiloride combination carrying a significantly higher risk than all other diuretics (P < 0.01).
Attributable clinical symptoms occurred in 61% of cases, 9 admissions were caused solely by hyponatraemia, and unit mortality doubled among hyponatraemic patients.

Cite This Study

Sunderam et al. (1983) studied this question.

synapsesocial.com/papers/6a758aa01a44875efa5ffca8 https://doi.org/10.1093/ageing/12.1.77

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Implication

Observational study reveals high rates of drug-induced hyponatraemia and doubled mortality in geriatric in-patients, highlighting the risks of diuretic therapy.

Hyponatraemia in the Elderly

Discussion

Member takes

Implication

Key Points

Cite This Study

Hyponatraemia in the Elderly

Discussion

Member takes

Implication

Key Points

Cite This Study

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