Why the study?
Does withdrawal of digoxin therapy reduce unnecessary medication use in geriatric patients without clear indications?
Does withdrawal of digoxin therapy reduce unnecessary medication use in geriatric patients without clear indications?
Digoxin can be safely withdrawn in a large majority of geriatric patients who lack clear indications for its continued use.
May support deprescribing digoxin in select geriatric patients; leaves open need for randomized confirmation.
Digoxin therapy was withdrawn over a four-year period in the geriatric wards of Skellefteå Hospital, if the indications for it were not clear, the medication was of doubtful value and there were no contraindications to withdrawal. Contraindications comprised symptoms of cardiac failure at rest or during light physical activity, X-ray signs of pulmonary congestion, a proven need for digoxin therapy following earlier withdrawal, or atrial fibrillation with a ventricular rate higher than 95 beats/min. A patient, who within two months presented signs of cardiac failure or an arrhythmia requiring digoxin, was considered to be in need of digoxin. Digoxin was withdrawn from a total of 141 patients, of whom 134 were examined after two months. According to our criteria, 108 (81%) of these 134 patients did not require digoxin treatment.
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Boman et al. (1981) studied this question.
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