What question did this study set out to answer?

To examine the sex-specific correlation between serum uric acid levels and cardiovascular risk factors, including obesity, hypertension, dyslipidemia, and diabetes mellitus.

January 1, 2004Hypertension Research

Hyperuricemia and Cardiovascular Risk Factor Clustering in a Screened Cohort in Okinawa, Japan

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Authors

KNKazufumi Nagahama KIKunitoshi Iseki TITaku Inoue

Discussion

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Overview

Cohort study reveals significant clustering of cardiovascular risk factors in individuals with hyperuricemia, indicating a shared metabolic burden.

Key Points

To examine the sex-specific correlation between serum uric acid levels and cardiovascular risk factors, including obesity, hypertension, dyslipidemia, and diabetes mellitus.
Cross-sectional study of 9,914 individuals (6,163 men and 3,751 women, aged 18 to 89 years) screened at the Okinawa General Health Maintenance Association in Japan.
Defined hyperuricemia as serum uric acid levels ≥7.0 mg/dL in men and ≥6.0 mg/dL in women.
In men, hyperuricemia was positively associated with obesity (OR 1.75, 95% CI 1.56–1.97), hypertension (OR 1.42, 95% CI 1.25–1.62), hypercholesterolemia (OR 1.16, 95% CI 1.02–1.30), and hypertriglyceridemia (OR 1.80, 95% CI 1.60–2.03), and inversely associated with diabetes mellitus (OR 0.61, 95% CI 0.49–0.75).
In women, hyperuricemia was associated with obesity (OR 2.02, 95% CI 1.62–2.53), hypertension (OR 1.64, 95% CI 1.29–2.10), hypercholesterolemia (OR 1.31, 95% CI 1.04–1.65), and hypertriglyceridemia (OR 1.95, 95% CI 1.51–2.51).
Coexistence of two or more cardiovascular risk factors occurred significantly more often in hyperuricemic individuals than non-hyperuricemic individuals (63.8% vs. 43.2% in men; 58.9% vs. 27.6% in women).

Cite This Study

Nagahama et al. (2004) studied this question.

synapsesocial.com/papers/6a758b8be42ca79ec1e72623 https://doi.org/10.1291/hypres.27.227

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January 1, 2004Hypertension Research

Hyperuricemia and Cardiovascular Risk Factor Clustering in a Screened Cohort in Okinawa, Japan

View Full Paper

Ask AI

Bookmark

Authors

KNKazufumi Nagahama KIKunitoshi Iseki TITaku Inoue

Discussion

Member takes

Overview

Cohort study reveals significant clustering of cardiovascular risk factors in individuals with hyperuricemia, indicating a shared metabolic burden.

Key Points

To examine the sex-specific correlation between serum uric acid levels and cardiovascular risk factors, including obesity, hypertension, dyslipidemia, and diabetes mellitus.
Cross-sectional study of 9,914 individuals (6,163 men and 3,751 women, aged 18 to 89 years) screened at the Okinawa General Health Maintenance Association in Japan.
Defined hyperuricemia as serum uric acid levels ≥7.0 mg/dL in men and ≥6.0 mg/dL in women.
In men, hyperuricemia was positively associated with obesity (OR 1.75, 95% CI 1.56–1.97), hypertension (OR 1.42, 95% CI 1.25–1.62), hypercholesterolemia (OR 1.16, 95% CI 1.02–1.30), and hypertriglyceridemia (OR 1.80, 95% CI 1.60–2.03), and inversely associated with diabetes mellitus (OR 0.61, 95% CI 0.49–0.75).
In women, hyperuricemia was associated with obesity (OR 2.02, 95% CI 1.62–2.53), hypertension (OR 1.64, 95% CI 1.29–2.10), hypercholesterolemia (OR 1.31, 95% CI 1.04–1.65), and hypertriglyceridemia (OR 1.95, 95% CI 1.51–2.51).
Coexistence of two or more cardiovascular risk factors occurred significantly more often in hyperuricemic individuals than non-hyperuricemic individuals (63.8% vs. 43.2% in men; 58.9% vs. 27.6% in women).

Cite This Study

Nagahama et al. (2004) studied this question.

synapsesocial.com/papers/6a758b8be42ca79ec1e72623 https://doi.org/10.1291/hypres.27.227

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