Population
Theoretical model of blood vessels comprising seven segments based on experimental data from isolated vessels.
Comparison
Theoretical modeling of myogenic… vs Model with constant vascular smooth muscle…
Design
Preclinical
Authors
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Supports metabolic-myogenic integration for autoregulation; extends computational models but leaves open human translation.
A theoretical model demonstrates that the combined effects of myogenic and metabolic regulation are necessary to overcome shear-induced vasodilation and achieve physiological blood flow autoregulation.
Carlson et al. (2008) studied this question.
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