Why the study?
Does rhein improve hepatic steatosis, insulin resistance, and cytokine imbalance in diet-induced obese mice?
Does rhein improve hepatic steatosis, insulin resistance, and cytokine imbalance in diet-induced obese mice?
Rhein ameliorates NAFLD and associated metabolic disorders in diet-induced obese mice through LXR-mediated pathways and immunomodulation.
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May benefit DIO mice with NAFLD; leaves open translation to human metabolic disease.
Sheng et al. (2011) studied this question.
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