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April 20, 2020International Journal of Environmental Research and Public HealthOpen Access

A Metabolically Healthy Profile Is a Transient Stage When Exercise and Diet Are Not Supervised: Long-Term Effects in the EXERDIET-HTA Study

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Why the study?

Achieving and maintaining a metabolically healthy overweight/obese state should be a key treatment goal in individuals with primary hypertension, obesity, and physical inactivity.

Does supervised aerobic exercise training and diet improve and maintain metabolic profiles compared to attentional control in physically inactive individuals with obesity and hypertension?

Population

219 overweight/obese, physically inactive individuals with primary hypertension

Comparison

16-week supervised aerobic exercise training plus hypocaloric diet vs attentional control plus hypocaloric diet

Design

Randomized controlled trial

Follow-up

16 weeks plus 6 months

Authors

PCPablo CorresSFSimon FryerAAAitor Martínez Aguirre-Betolaza

Discussion

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Overview

May support supervised exercise plus diet for shifting MUO toward MHO in inactive HTN patients; hypothesis-generating, needs confirmation in randomized trials.

Structured PICO

Does supervised aerobic exercise training and diet improve and maintain metabolic profiles compared to attentional control in physically inactive individuals with obesity and hypertension?

P
Population
219 overweight/obese, physically inactive individuals with primary hypertension
I
Intervention
16-week supervised aerobic exercise training (SupExT) and hypocaloric diet, followed by 6 months of unsupervised diet and physical activity advice
C
Comparator
Attentional control (AC) and hypocaloric diet for 16 weeks, followed by 6 months of unsupervised diet and physical activity advice
O
Outcome
Differences in metabolic profiles (total cholesterol, alanine aminotransferase, glucose, C-reactive protein, systolic blood pressure, and cardiorespiratory fitness) at 16 weeks and after 6 months of unsupervised timesurrogate

Supervised exercise and diet significantly improve cardiometabolic health in obese hypertensive patients, but these benefits are lost after 6 months without supervision, highlighting the need for continuous supervised interventions.

Cite This Study

Corres et al. (2020) studied this question.

synapsesocial.com/papers/6a758c3ffbccc8f4fd160bf3https://doi.org/10.3390/ijerph17082830
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Long-Term Effects in the EXERDIET-HTA Study: Supervised Exercise Training <i>vs</i>. Physical Activity Advice2019 · 9 citations
  2. 2The Effects of Exercise Training on the Traditional Lipid Profile and Beyond2014 · 145 citations
  3. 3The Relationship between the Blood Pressure Responses to Exercise following Training and Detraining Periods2014 · 65 citations
  4. 4Importance of Assessing Cardiorespiratory Fitness in Clinical Practice: A Case for Fitness as a Clinical Vital Sign: A Scientific Statement From the American Heart Association2016 · 2,509 citations
  5. 52017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines2017 · 7,461 citations