Magnesium Depletion in Man

Article1 February 1959MAGNESIUM DEPLETION IN MANRUSSELL E. RANDALL JR., ELSIE C. ROSSMEISL, KENNETH H. BLEIFERRUSSELL E. RANDALL JR., ELSIE C. ROSSMEISL, KENNETH H. BLEIFERAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-50-2-257 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe discovery of a neuromuscular disorder in animals specifically related to a deficiency of magnesium1-9has led to investigation of this ion in various clinical disorders in man.10-31Studies have been seriously handicapped by several factors. The quantitative determination of magnesium has proved troublesome, particularly with the older precipitation methods.32-34The current methods employing colorimetric technics,35-37and the newer methods employing flame photometry,38spectrography39-41and versene chelation,42-44are rapidly overcoming this barrier. 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Author, Article, and Disclosure InformationAffiliations: *Presented at the Thirty-ninth Annual Session of The American College of Physicians, Atlantic City, New Jersey, May 1, 1958, under the title, "Low Serum Magnesium in Man."From the Medical Service and Research Laboratory, Boston Veterans Administration Hospital, and the Departments of Medicine, Boston University School of Medicine and Tufts University School of Medicine, Boston, Massachusetts.†Present address: 4167th USAF Hospital, Travis Air Force Base, California.Requests for reprints should be addressed to Secretary, Research Laboratory, Boston Veterans Administration Hospital, 150 South Huntington Avenue, Boston 30, Massachusetts. 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