May 1, 1994The Journal of PhysiologyOpen Access

Sympathetic activity recorded from the rat caudal ventral artery in vivo.

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Population

25 sodium pentobarbitone-anaesthetized, artificially ventilated and paralysed rats

Design

Preclinical

Authors

CJChristopher JohnsonRitsumeikan University MGMichael P. GilbeyUniversity College London

Discussion

Member takes

Implication

Advances sympathetic vasomotor single-unit mapping in vivo; leaves open translation to human cardiovascular control.

Structured PICO

Population

25 sodium pentobarbitone (alpha-chloralose supplemented)-anaesthetized, artificially ventilated and paralysed rats

Intervention

Focal recording technique of postganglionic sympathetic single unit activity at the level of the adventitia of the caudal ventral artery of the tail, with electrical stimulation of the lumbar sympathetic chain, hexamethonium administration, and whole-body warming

Outcome

Characteristics of sympathetic single unit activity (activation, modulation, firing patterns)surrogate

This study provides the first in vivo analysis of single unit activity from sympathetic fibres innervating an identified blood vessel, demonstrating respiratory modulation and temperature sensitivity.

Cite This Study

Johnson et al. (1994) studied this question.

synapsesocial.com/papers/6a7591e3756843cacbb21637 https://doi.org/10.1113/jphysiol.1994.sp020145

View Full Paper

Ask AI

Bookmark

Sympathetic activity recorded from the rat caudal ventral artery in vivo.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Sympathetic activity recorded from the rat caudal ventral artery in vivo.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider