Key result
Of 210 sympathetic preganglionic neurons observed in anesthetized cats, 21% were spontaneously active with a mean discharge rate of 1.4 spikes/s.
This preclinical study demonstrates that spontaneous activity of sympathetic preganglionic neurons in cats is largely irregular, endogenous, and responsive to physiological stressors like hemorrhage and pressor drugs.
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May not translate to human sympathetic regulation; leaves open the contribution of spontaneous preganglionic firing to cardiovascular control.
Canio Polosa (1968) studied this question. Of 210 sympathetic preganglionic neurons observed in anesthetized cats, 21% were spontaneously active with a mean discharge rate of 1.4 spikes/s.
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