Key result
The discharge pattern of sympathetic preganglionic neurones is shaped by synaptic inputs, membrane properties, and local factors, with in vivo spikes generated solely from synaptic potentials.
Population
Sympathetic preganglionic neurones (SPNs) within the thoracic spinal cord (in vivo and in vitro models)
Design
Review
Authors
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In vitro SPN findings warrant clinical caution; leaves open synaptic mechanisms of sympathetic discharge in hypertension.
This paper summarizes the integrative physiological properties of sympathetic preganglionic neurons, highlighting their regulation by synaptic inputs, membrane properties, and resistance to hypoxia.
Dembowsky et al. (1995) conducted a review in Sympathetic preganglionic neurone physiology. The discharge pattern of sympathetic preganglionic neurones is shaped by synaptic inputs, membrane properties, and local factors, with in vivo spikes generated solely from synaptic potentials.
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